Independent Research Groups / Human Electrophysiology and AI
We investigate how neural activity gives rise to human cognition and behavior, and how its disruption leads to neurological disease such as epilepsy.
Human Electrophysiology and AI
Connecting the Hertie AI and the Hertie Institute for Clinical Brain Research (HIH), our group explores how neural activity gives rise to human cognition and behavior, and how disruptions of these processes lead to neurological disease. Our mission is to integrate clinical neuroscience and artificial intelligence to advance both fundamental discoveries about the human brain and innovative solutions for neurological care.
We investigate the human brain using uniquely rich, high-dimensional datasets from epilepsy patients, combining invasive recordings—including single-neuron activity, local field potentials, and intracranial EEG—with multimodal clinical data, including neurological symptom descriptions, neuroimaging, and video recordings.
Our interdisciplinary team brings together expertise in clinical neurology, epileptology, psychology, systems neuroscience, and machine learning to develop novel computational approaches for multimodal data analysis. Using advanced AI methods such as recurrent neural networks and large language models, we investigate the neural mechanisms of memory and perception, decode behavioral states from brain activity, identify clinically meaningful biomarkers, and develop automated diagnostic tools for neurological disorders.
By serving as a bridge between clinical neuroscience and artificial intelligence, our research creates a two-way exchange: clinical challenges inspire new computational methods, while advances in AI generate clinically translatable insights that deepen our understanding of the human brain and ultimately improve patient care.
